Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis

Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis

ABSTRACT Clofazimine (CFZ) has been repurposed for treating tuberculosis (TB), especially multidrug-resistant tuberculosis (MDR-TB). However, the mechanisms of resistance to clofazimine are poorly understood. We previously reported a mutation located in the intergenic region of Rv1453 that was linke...

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Bibliographic Details
Main Authors: Lei Zhang, Ye Zhang, Yuanyuan Li, Fengmin Huo, Xi Chen, Hui Zhu, Shaochen Guo, Lei Fu, Bin Wang, Yu Lu
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
clofazimine
Rv1453
drug resistant
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00002-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00002-23

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