Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor.

Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood. Activated platelets can release pro-fibrotic mediators that have the potential to contribute to lung fibrosis. We determ...

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Bibliographic Details
Main Authors: Michael G Crooks, Ahmed Fahim, Khalid M Naseem, Alyn H Morice, Simon P Hart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206466?pdf=render