Association of <i>bla</i><sub>VIM-2</sub>, <i>bla</i><sub>PDC-35</sub>, <i>bla</i><sub>OXA-10,</sub> <i>bla</i><sub>OXA-488</sub> and <i>bla</i><sub>VEB-9</sub> β-Lactamase Genes with Resistance to Ceftazidime–Avibactam and Ceftolozane–Tazobactam in Multidrug-Resistant <i>Pseudomonas aeruginosa</i>

Association of <i>bla</i><sub>VIM-2</sub>, <i>bla</i><sub>PDC-35</sub>, <i>bla</i><sub>OXA-10,</sub> <i>bla</i><sub>OXA-488</sub> and <i>bla</i><sub>VEB-9</sub> β-Lactamase Genes with Resistance to Ceftazidime–Avibactam and Ceftolozane–Tazobactam in Multidrug-Resistant <i>Pseudomonas aeruginosa</i>

Ceftazidime–avibactam and ceftolozane–tazobactam are approved for the treatment of complicated Gram-negative bacterial infections including multidrug-resistant (MDR) <i>Pseudomonas aeruginosa</i>. Resistance to both agents has been reported, but the underlying mechanisms have not been fu...

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Bibliographic Details
Main Authors: Mazen A. Sid Ahmed, Faisal Ahmad Khan, Hamad Abdel Hadi, Sini Skariah, Ali A. Sultan, Abdul Salam, Abdul Latif Al Khal, Bo Söderquist, Emad Bashir Ibrahim, Ali S. Omrani, Jana Jass
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antibiotics
Subjects:
<i>P. aeruginosa</i>
β-lactamases
ceftazidime–avibactam
ceftolozane–tazobactam
antimicrobial resistance
PDC-35
Online Access:https://www.mdpi.com/2079-6382/11/2/130

Internet

https://www.mdpi.com/2079-6382/11/2/130

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