Navigating the Complex Landscape of Fibrodysplasia Ossificans Progressiva: From Current Paradigms to Therapeutic Frontiers

Navigating the Complex Landscape of Fibrodysplasia Ossificans Progressiva: From Current Paradigms to Therapeutic Frontiers

Fibrodysplasia ossificans progressiva (FOP) is an enigmatic, ultra-rare genetic disorder characterized by progressive heterotopic ossification, wherein soft connective tissues undergo pathological transformation into bone structures. This incapacitating process severely limits patient mobility and p...

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Bibliographic Details
Main Authors: Saeed Anwar, Toshifumi Yokota
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Genes
Subjects:
fibrodysplasia ossificans progressiva (FOP)
ultra-rare disorders
heterotopic ossification
bone morphogenetic proteins (BMPs)
ACVR1
targeted therapy
Online Access:https://www.mdpi.com/2073-4425/14/12/2162

Internet

https://www.mdpi.com/2073-4425/14/12/2162

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