Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

<p>Abstract</p> <p>Background</p> <p>Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). Methods developed fo...

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Bibliographic Details
Main Authors: Juliusson Gunnar, Lindgren David, Vallon-Christersson Johan, Staaf Johan, Rosenquist Richard, Höglund Mattias, Borg Åke, Ringnér Markus
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/409

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http://www.biomedcentral.com/1471-2105/9/409

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