Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

AbstractTrypanosomiasis is a protozoan disease transmitted via Trypanosoma brucei. This study aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of Thunbergia grandifolia leaves. The liquid chromatography-high resolution electrospray ionisation mass spectrometry...

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Bibliographic Details
Main Authors: Heba A. S. El-Nashar, Ahmed M. Sayed, Hany A. M. El-Sherief, Mostafa E. Rateb, Lina Akil, Ibrahim Khadra, Taghreed A. Majrashi, Sara T. Al-Rashood, Faizah A. Binjubair, Mahmoud A. El Hassab, Wagdy M. Eldehna, Usama Ramadan Abdelmohsen, Nada M. Mostafa
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Trypanosoma brucei
Thunbergia grandifolia
LC-MS
in silico
inverse docking
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2199950

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2023.2199950

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