Effects of super-enhancers in cancer metastasis: mechanisms and therapeutic targets

Effects of super-enhancers in cancer metastasis: mechanisms and therapeutic targets

Abstract Metastasis remains the principal cause of cancer-related lethality despite advancements in cancer treatment. Dysfunctional epigenetic alterations are crucial in the metastatic cascade. Among these, super-enhancers (SEs), emerging as new epigenetic regulators, consist of large clusters of re...

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Bibliographic Details
Main Authors: Shenglan Liu, Wei Dai, Bei Jin, Feng Jiang, Hao Huang, Wen Hou, Jinxia Lan, Yanli Jin, Weijie Peng, Jingxuan Pan
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Molecular Cancer
Subjects:
Super-enhancers
Metastasis
Molecular mechanisms
Therapeutic targets
Online Access:https://doi.org/10.1186/s12943-024-02033-8

Internet

https://doi.org/10.1186/s12943-024-02033-8

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