A novel tyrosine tRNA-derived fragment, tRFTyr, induces oncogenesis and lactate accumulation in LSCC by interacting with LDHA

A novel tyrosine tRNA-derived fragment, tRFTyr, induces oncogenesis and lactate accumulation in LSCC by interacting with LDHA

Abstract Background Transfer (t)RNA-derived small RNA (tsRNA), generated from precursor or mature tRNA, is a new type of small non-coding RNA (sncRNA) that has recently been shown to play a vital role in human cancers. However, its role in laryngeal squamous cell carcinoma (LSCC) remains unclear. Me...

Full description

Bibliographic Details
Main Authors: Rui Zhao, Zhenming Yang, Bo Zhao, Wenjing Li, Yaohui Liu, Xiaoxue Chen, Jing Cao, Jiarui Zhang, Yan Guo, Licheng Xu, Jinpeng Wang, Yanan Sun, Ming Liu, Linli Tian
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
tsRNAs
tRFTyr
LDHA
Lactate
LSCC
Online Access:https://doi.org/10.1186/s11658-023-00463-8

Internet

https://doi.org/10.1186/s11658-023-00463-8

Similar Items