Directed Evolution of a Genetically Encoded Bioluminescent Ca<sup>2+</sup> Sensor

The use of genetically encoded fluorescent sensors for the calcium ion (Ca<sup>2+</sup>) has revolutionized neuroscience research by allowing for the recording of dozens of neurons at the single-cell level in living animals. However, fluorescence imaging has some limitations such as the...

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Bibliographic Details
Main Authors: Yufeng Zhao, Sungmoo Lee, Robert E. Campbell, Michael Z. Lin
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Engineering Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4591/35/1/20