Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects
Abstract Background Congenital heart defects (CHD) are structural defects of the heart affecting approximately 1% of newborns. They exhibit low penetrance and non-Mendelian patterns of inheritance as varied and complex traits. While genetic factors are known to play an important role in the developm...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-024-10172-x |