Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance
Abstract Background Efficient bioethanol production from hemicellulose feedstocks by Saccharomyces cerevisiae requires xylose utilization. Whereas S. cerevisiae does not metabolize xylose, engineered strains that express xylose isomerase can metabolize xylose by converting it to xylulose. For this,...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
|
Series: | Biotechnology for Biofuels |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13068-019-1643-0 |