Trace Metal Impurities Effects on the Formation of [<sup>64</sup>Cu]Cu-diacetyl-bis(<i>N</i><sup>4</sup>-methylthiosemicarbazone) ([<sup>64</sup>Cu]Cu-ATSM)

Trace Metal Impurities Effects on the Formation of [<sup>64</sup>Cu]Cu-diacetyl-bis(<i>N</i><sup>4</sup>-methylthiosemicarbazone) ([<sup>64</sup>Cu]Cu-ATSM)

[<sup>64</sup>Cu]Cu-diacetyl-bis(<i>N</i><sup>4</sup>-methylthiosemicarbazone) ([<sup>64</sup>Cu]Cu-ATSM) is a radioactive hypoxia-targeting therapeutic agent being investigated in clinical trials for malignant brain tumors. For the quality management...

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Bibliographic Details
Main Authors: Mitsuhiro Shinada, Hisashi Suzuki, Masayuki Hanyu, Chika Igarashi, Hiroki Matsumoto, Masashi Takahashi, Fukiko Hihara, Tomoko Tachibana, Chizuru Sogawa, Ming-Rong Zhang, Tatsuya Higashi, Hidemitsu Sato, Hiroaki Kurihara, Yukie Yoshii, Yoshihiro Doi
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceuticals
Subjects:
trace metal impurities
[<sup>64</sup>Cu]Cu-ATSM
quality management
Online Access:https://www.mdpi.com/1424-8247/17/1/10

Internet

https://www.mdpi.com/1424-8247/17/1/10

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