Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies
Abstract Host organisms use different innate immune mechanisms to defend against pathogenic infections, while tight control of innate immunity is essential for proper immune induction and balance. Here, we reported that apoptotic induction or caspase-3 overexpression caused dramatic reduction of dif...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05156-2 |