GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

Summary: Neurotransmitter receptors are involved in cancer progression. Among them, the heterodimeric GABAB receptor, activated by the main inhibitory neurotransmitter GABA, is composed of the transmembrane GABAB1 and GABAB2 subunits. The oncogenic role of the isoform GABAB1e (GB1e) containing only...

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Bibliographic Details
Main Authors: Bo Wei, Yini Zhu, Peng Yang, Yong Han, Suyun Wang, Xiaomei Wang, Shuai Xia, Xiaoguang Song, Zhongling Zhang, Sheng Wang, Philippe Rondard, Jean-Philippe Pin, Xinnong Jiang, Jianfeng Liu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012803

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221012803

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