Total network controllability analysis discovers explainable drugs for Covid-19 treatment

Abstract Background The active pursuit of network medicine for drug repurposing, particularly for combating Covid-19, has stimulated interest in the concept of structural controllability in cellular networks. We sought to extend this theory, focusing on the defense rather than control of the cell ag...

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Bibliographic Details
Main Authors: Xinru Wei, Chunyu Pan, Xizhe Zhang, Weixiong Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Biology Direct
Subjects:
Online Access:https://doi.org/10.1186/s13062-023-00410-9