The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels

Abstract T-type calcium channels are known molecular targets of certain phytocannabinoids and endocannabinoids. Here we explored the modulation of Cav3.2 T-type calcium channels by terpenes derived from cannabis plants. A screen of eight commercially available terpenes revealed that camphene and alp...

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Bibliographic Details
Main Authors: Vinicius M. Gadotti, Sun Huang, Gerald W. Zamponi
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00876-6