<i>Bordetella</i> Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein

<i>Bordetella</i> Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein

The mucus layer protects airway epithelia from damage by noxious agents. Intriguingly, <i>Bordetella pertussis</i> bacteria provoke massive mucus production by nasopharyngeal epithelia during the initial coryza-like catarrhal stage of human pertussis and the pathogen transmits in mucus-c...

Full description

Bibliographic Details
Main Authors: Anna Malandra, Waheed Ur Rahman, Nela Klimova, Gaia Streparola, Jana Holubova, Adriana Osickova, Simone Bariselli, Peter Sebo, Radim Osicka
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
adenylate cyclase toxin
<i>Bordetella</i>
cAMP
CREB
epithelium
mucin
Online Access:https://www.mdpi.com/1422-0067/22/16/9064

Internet

https://www.mdpi.com/1422-0067/22/16/9064

Similar Items