The heterogeneity of asymmetric tau distribution is associated with an early age at onset and poor prognosis in Alzheimer’s disease

Purpose: Left-right asymmetry, an important feature of brain development, has been implicated in neurodegenerative diseases, although it’s less discussed in typical Alzheimer’s disease (AD). We sought to investigate whether asymmetric tau deposition plays a potential role in AD heterogeneity. Method...

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Bibliographic Details
Main Authors: Jiaying Lu, Zhengwei Zhang, Ping Wu, Xiaoniu Liang, Huiwei Zhang, Jimin Hong, Christoph Clement, Tzu-Chen Yen, Saineng Ding, Min Wang, Zhenxu Xiao, Axel Rominger, Kuangyu Shi, Yihui Guan, Chuantao Zuo, Qianhua Zhao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223001055