An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery

An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery

Human stem cell-derived neurons are increasingly considered powerful models in drug discovery and disease modeling, despite limited characterization of their molecular properties. Here, we have conducted a detailed study of the properties of a commercial human induced Pluripotent Stem Cell (iPSC)-de...

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Bibliographic Details
Main Authors: Robert F. Halliwell, Hamed Salmanzadeh, Leanne Coyne, William S. Cao
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
neurotransmitter receptors
ion channels
multi-electrode array
patch-clamp
Online Access:https://www.mdpi.com/2073-4409/10/8/1953

Internet

https://www.mdpi.com/2073-4409/10/8/1953

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