Patterns of white matter damage are non-random and associated with cognitive function in secondary progressive multiple sclerosis

Patterns of white matter damage are non-random and associated with cognitive function in secondary progressive multiple sclerosis

In multiple sclerosis (MS), white matter damage is thought to contribute to cognitive dysfunction, which is especially prominent in secondary progressive MS (SPMS). While studies in healthy subjects have revealed patterns of correlated fractional anisotropy (FA) across white matter tracts, little is...

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Bibliographic Details
Main Authors: K.A. Meijer, M. Cercignani, N. Muhlert, V. Sethi, D. Chard, J.J.G. Geurts, O. Ciccarelli
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:NeuroImage: Clinical
Subjects:
Secondary progressive multiple sclerosis
Cognition
MRI
Diffusion tensor imaging
Tract-based spatial statistics
Independent component analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158216301073

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http://www.sciencedirect.com/science/article/pii/S2213158216301073

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