Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2

Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2

Hepatitis B virus (HBV) specifically infects human hepatocytes and increases the risks of cirrhosis and liver cancer. Currently, nucleic acid analogs are the main therapeutics for chronic hepatitis caused by HBV infection. Although nucleic acid analogs can eliminate HBV DNA by inhibiting HBV reverse...

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Bibliographic Details
Main Authors: Anna Nakanishi, Hiroki Okumura, Tadahiro Hashita, Aya Yamashita, Yuka Nishimura, Chihiro Watanabe, Sakina Kamimura, Sanae Hayashi, Shuko Murakami, Kyoko Ito, Takahiro Iwao, Akari Ikeda, Tomoyasu Hirose, Toshiaki Sunazuka, Yasuhito Tanaka, Tamihide Matsunaga
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
hepatitis B virus
ivermectin
importin α/β
karyopherin α
hepatitis B surface antigen
hepatitis B core protein
Online Access:https://www.mdpi.com/1999-4915/14/11/2468

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https://www.mdpi.com/1999-4915/14/11/2468

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