Structural basis of ion uptake in copper-transporting P1B-type ATPases

P1B-type ATPases export excess transition metals from cells. Here, the authors report a molecular structure of CopA, a coppertransporting P1B-ATPase from A. fulgidus, in an inward-facing E1 conformation.

Bibliographic Details
Main Authors: Nina Salustros, Christina Grønberg, Nisansala S. Abeyrathna, Pin Lyu, Fredrik Orädd, Kaituo Wang, Magnus Andersson, Gabriele Meloni, Pontus Gourdon
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32751-w