Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study

BackgroundThe interleukin-1 pathway has been linked to pancreatic diseases. We applied the Mendelian randomization approach to explore whether higher interleukin-1 receptor antagonist (IL-1RA) levels reduce the risk of acute and chronic pancreatitis and pancreatic cancer.MethodsGenetic variants asso...

Full description

Bibliographic Details
Main Authors: Shuai Yuan, Yuyang Miao, Xixian Ruan, Jie Chen, Xue Li, Susanna C. Larsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1240754/full