Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study

Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study

BackgroundThe interleukin-1 pathway has been linked to pancreatic diseases. We applied the Mendelian randomization approach to explore whether higher interleukin-1 receptor antagonist (IL-1RA) levels reduce the risk of acute and chronic pancreatitis and pancreatic cancer.MethodsGenetic variants asso...

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Bibliographic Details
Main Authors:	Shuai Yuan, Yuyang Miao, Xixian Ruan, Jie Chen, Xue Li, Susanna C. Larsson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Series:	Frontiers in Immunology
Subjects:	interleukin-1 receptor antagonist mendelian randomization pancreatic disease acute pancreatitis (AP) chronic pancreatitis pancreatic cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1240754/full

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