Elevated mutagenesis does not explain the increased frequency of antibiotic resistant mutants in starved aging colonies.

The frequency of mutants resistant to the antibiotic rifampicin has been shown to increase in aging (starved), compared to young colonies of Escherichia coli. These increases in resistance frequency occur in the absence of any antibiotic exposure, and similar increases have also been observed in res...

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Bibliographic Details
Main Authors: Sophia Katz, Ruth Hershberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3828146?pdf=render