Considerations for Applying Route-to-Route Extrapolation to Assess the Safety of Oral Exposure to Substances

The safety evaluation of oral exposure to substances, such as food ingredients, additives, and their constituents, relies primarily on a careful evaluation and analysis of data from oral toxicity studies. When relevant oral toxicity studies are unavailable or may have significant data gaps that make...

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Bibliographic Details
Main Authors: Shruti V. Kabadi, Jeffrey Fisher, Benjamin Hung, Jason Aungst
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/1/5