Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment

Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment

Annexin A1 (AnxA1) is a pleiotropic protein that exerts essential roles in breast cancer (BC) growth and aggressiveness. In our previous work, we described the autocrine signaling of AnxA1 through formyl peptide receptor 1 (FPR1) in the triple-negative (TN) BC cell line, MDA-MB-231. Here, we aimed t...

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Bibliographic Details
Main Authors: Lara Vecchi, Sara Teixeira Soares Mota, Mariana Alves Pereira Zóia, Isabella Castro Martins, Jessica Brito de Souza, Tiago Góss Santos, Adriano de Oliveira Beserra, Victor Piana de Andrade, Luiz Ricardo Goulart, Thaise Gonçalves Araújo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Annexin A1
autocrine signaling
breast cancer
formyl peptide receptor
IL-6
STAT3
Online Access:https://www.mdpi.com/2073-4409/11/10/1705

Internet

https://www.mdpi.com/2073-4409/11/10/1705

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