Nerve ECM and PLA-PCL based electrospun bilayer nerve conduit for nerve regeneration

Introduction: The porcine nerve-derived extracellular matrix (ECM) fabricated as films has good performance in peripheral nerve regeneration. However, when constructed as conduits to bridge nerve defects, ECM lacks sufficient mechanical strength.Methods: In this study, a novel electrospun bilayer-st...

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Bibliographic Details
Main Authors: Xiaoyan Mao, Ting Li, Junqiu Cheng, Meihan Tao, Zhiyuan Li, Yizhan Ma, Rabia Javed, Jie Bao, Fang Liang, Weihong Guo, Xiaohong Tian, Jun Fan, Tianhao Yu, Qiang Ao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1103435/full