Development and Stability of a New Formulation of Pentobarbital Suppositories for Paediatric Procedural Sedation

Development and Stability of a New Formulation of Pentobarbital Suppositories for Paediatric Procedural Sedation

Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred for infants and children, no pentobarbital suppositories are marketed, and therefore they must be prepared by compounding pharmacies. In this...

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Bibliographic Details
Main Authors: Matthieu Lebrat, Yassine Bouattour, Coralie Gaudet, Mouloud Yessaad, Mireille Jouannet, Mathieu Wasiak, Imen Dhifallah, Eric Beyssac, Ghislain Garrait, Philip Chennell, Valérie Sautou
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
pentobarbital
formulation
suppositories
stability
sedation
Online Access:https://www.mdpi.com/1999-4923/15/3/755

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https://www.mdpi.com/1999-4923/15/3/755

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