Engineered Bacillus subtilis for the de novo production of 2′-fucosyllactose

Engineered Bacillus subtilis for the de novo production of 2′-fucosyllactose

Abstract Background The most abundant human milk oligosaccharide in breast milk, 2′-fucosyllactose (2′-FL), has been approved as an additive to infant formula due to its multifarious nutraceutical and pharmaceutical functions in promoting neonate health. However, the low efficiency of de novo synthe...

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Bibliographic Details
Main Authors: Quanwei Zhang, Zhenmin Liu, Hongzhi Xia, Ziyang Huang, Yonglian Zhu, Linfeng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Microbial Cell Factories
Subjects:
Bacillus subtilis
De novo pathway
2′-fucosyllactose
GDP- L -fucose
Online Access:https://doi.org/10.1186/s12934-022-01838-w

Internet

https://doi.org/10.1186/s12934-022-01838-w

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