CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication

CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication

Here the authors report the construction of a genome-scale porcine CRISPR/Cas9 library, called PigGeCKO, for screening and analyses of host resistance genes and factors associated with Japanese encephalitis virus replication.

Bibliographic Details
Main Authors: Changzhi Zhao, Hailong Liu, Tianhe Xiao, Zichang Wang, Xiongwei Nie, Xinyun Li, Ping Qian, Liuxing Qin, Xiaosong Han, Jinfu Zhang, Jinxue Ruan, Mengjin Zhu, Yi-Liang Miao, Bo Zuo, Kui Yang, Shengsong Xie, Shuhong Zhao
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18936-1

Internet

https://doi.org/10.1038/s41467-020-18936-1

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