Probing the dynamic landscape of peptides in molecular assemblies by synergized NMR experiments and MD simulations

Abstract Peptides or proteins containing small biomolecular aggregates, such as micelles, bicelles, droplets and nanodiscs, are pivotal in many fields ranging from structural biology to pharmaceutics. Monitoring dynamics of such systems has been limited by the lack of experimental methods that could...

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Bibliographic Details
Main Authors: Ricky Nencini, Morgan L. G. Regnier, Sofia M. Backlund, Efstathia Mantzari, Cory D. Dunn, O. H. Samuli Ollila
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01115-4