MicroRNA-497-5p stimulates osteoblast differentiation through HMGA2-mediated JNK signaling pathway

MicroRNA-497-5p stimulates osteoblast differentiation through HMGA2-mediated JNK signaling pathway

Abstract Background Osteoporosis (OP) has the characteristics of the decline in bone mineral density and worsening of bone quality, contributing to a higher risk of fractures. Some microRNAs (miRNAs) have been validated as possible mediators of osteoblast differentiation. We herein aimed to clarify...

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Bibliographic Details
Main Authors: Huiqing Zhao, Yexiang Yang, Yang Wang, Xiaolei Feng, Adi Deng, Zhaolan Ou, Biying Chen
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
MicroRNA-497-5p
HMGA2
JNK pathway
Osteoporosis
Osteoblasts
Online Access:http://link.springer.com/article/10.1186/s13018-020-02043-4

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http://link.springer.com/article/10.1186/s13018-020-02043-4

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