<i>N</i>-Derivatives of (<i>Z</i>)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1<i>H</i>-indole-2-carboxylates as Antimicrobial Agents—In Silico and In Vitro Evaluation

<i>N</i>-Derivatives of (<i>Z</i>)-Methyl 3-(4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-1<i>H</i>-indole-2-carboxylates as Antimicrobial Agents—In Silico and In Vitro Evaluation

Herein, we report the experimental evaluation of the antimicrobial activity of seventeen new (<i>Z</i>)-methyl 3-(4-oxo-2-thioxothiazolidin-5-ylidene)methyl)-1<i>H</i>-indole-2-carboxylate derivatives. All tested compounds exhibited antibacterial activity against eight Gram-p...

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Bibliographic Details
Main Authors: Anthi Petrou, Athina Geronikaki, Victor Kartsev, Antonios Kousaxidis, Aliki Papadimitriou-Tsantarliotou, Marina Kostic, Marija Ivanov, Marina Sokovic, Ioannis Nicolaou, Ioannis S. Vizirianakis
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceuticals
Subjects:
indole
rhodanine
antimicrobial
antibacterial activity
antifungal activity
molecular docking
Online Access:https://www.mdpi.com/1424-8247/16/1/131

Internet

https://www.mdpi.com/1424-8247/16/1/131

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