Melatonin or vitamin C attenuates lead acetate-induced testicular oxidative and inflammatory damage in mice by inhibiting oxidative stress mediated NF-κB signaling

Lead (Pb) acts as an environmental endocrine disruptor and has negative effects in animals; excessive accumulation of lead causes reproductive dysfunction in male animals. Oxidative stress plays a vital role in Pb-induced injury. However, the mechanisms underlying chronic testicular toxicity of Pb r...

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Bibliographic Details
Main Authors: Ze-Min Zhao, Su Mei, Qi-Yue Zheng, Jiao Wang, Yi-Ru Yin, Jiao-Jiao Zhang, Xian-Zhong Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323009855