Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.

Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.

Dilated cardiomyopathy, the most severe manifestation in chronic phase of Chagas disease, affects about 30% of patients and is characterized by myocardial dysfunction and interstitial fibrosis due to extracellular matrix (ECM) remodeling. ECM remodeling is regulated by proteolytic enzymes such as ma...

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Bibliographic Details
Main Authors: Nayara I Medeiros, Rafaelle C G Fares, Eliza P Franco, Giovane R Sousa, Rafael T Mattos, Ana T Chaves, Maria do Carmo P Nunes, Walderez O Dutra, Rodrigo Correa-Oliveira, Manoel O C Rocha, Juliana A S Gomes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5261563?pdf=render

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http://europepmc.org/articles/PMC5261563?pdf=render

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