Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.

Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.

Dilated cardiomyopathy, the most severe manifestation in chronic phase of Chagas disease, affects about 30% of patients and is characterized by myocardial dysfunction and interstitial fibrosis due to extracellular matrix (ECM) remodeling. ECM remodeling is regulated by proteolytic enzymes such as ma...

Full description

Bibliographic Details
Main Authors: Nayara I Medeiros, Rafaelle C G Fares, Eliza P Franco, Giovane R Sousa, Rafael T Mattos, Ana T Chaves, Maria do Carmo P Nunes, Walderez O Dutra, Rodrigo Correa-Oliveira, Manoel O C Rocha, Juliana A S Gomes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5261563?pdf=render

Similar Items

Similar Items