Structural Analysis of Human Fascin-1: Essential Protein for Actin Filaments Bundling

Fascin, a major actin cross-linking protein, is expressed in most vertebrate epithelial tissues. It organizes actin filaments into well-ordered bundles that are responsible for the extension of dynamic membrane protrusions, including microspikes, filopodia, and invadopodia from cell surfaces, which...

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Bibliographic Details
Main Authors: Jeong Min Chung, Osamu Sato, Reiko Ikebe, Sangmin Lee, Mitsuo Ikebe, Hyun Suk Jung
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/6/843