Mesangial cell-binding activity of serum immunoglobulin g in patients with lupus nephritis.

In vitro data showed that immunoglobulin G (IgG) from patients with lupus nephritis (LN) could bind to cultured human mesangial cells (HMC). The clinical relevance of such binding was unknown. Binding of IgG and subclasses was measured in 189 serial serum samples from 23 patients with Class III/IV±V...

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Bibliographic Details
Main Authors: Desmond Y H Yap, Susan Yung, Qing Zhang, Colin Tang, Tak Mao Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090162?pdf=render