Synthesis and conformational analysis of N-BOC-protected-3,5-bis(arylidene)-4-piperidone EF-24 analogs as anti-cancer agents

Synthesis and conformational analysis of N-BOC-protected-3,5-bis(arylidene)-4-piperidone EF-24 analogs as anti-cancer agents

Natural products and their analogs have been explored to stop the progression of cancer cells without unwanted side effects. Chalcones, compounds synthesized naturally in plants, have demonstrated potential as anti-cancer treatments. A library of bis-chalcones that are similar in structure to EF-24,...

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Bibliographic Details
Main Authors: Smith Robert B., Roberts William, Upenieks Mary, Gibson Maya Z., Wentzel Michael T., Grice Kyle A., Zingales Sarah K.
Format: Article
Language:English
Published: De Gruyter 2023-04-01
Series:Heterocyclic Communications
Subjects:
bis-chalcone
curcumin
anti-cancer
dynamic nmr
dft
Online Access:https://doi.org/10.1515/hc-2022-0162

Internet

https://doi.org/10.1515/hc-2022-0162

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