Promotion of the inflammatory response in mid colon of complement component 3 knockout mice

Abstract To determine whether complement component 3 (C3) deficiency affects its receptor downstream-mediated inflammatory response, the current study was undertaken to measure alterations in the inducible nitric oxide synthase (iNOS)‑mediated cyclooxygenase‑2 (COX‑2) induction pathway, inflammasome...

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Bibliographic Details
Main Authors: Yun Ju Choi, Ji Eun Kim, Su Jin Lee, Jeong Eun Gong, You Jeong Jin, Ho Lee, Dae Youn Hwang
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05708-8