A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function

The two homologous estrogen receptors ERα and ERβ exert distinct effects on their cognate tissues. Previous work from our laboratory identified an ERβ-specific phosphotyrosine residue that regulates ERβ transcriptional activity and antitumor function in breast cancer cells. To determine the physiolo...

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Bibliographic Details
Main Authors: Bin Yuan, Jing Yang, Louis Dubeau, Yanfen Hu, Rong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.649087/full