Transesterification Synthesis of Chloramphenicol Esters with the Lipase from Bacillus amyloliquefaciens

Transesterification Synthesis of Chloramphenicol Esters with the Lipase from Bacillus amyloliquefaciens

This work presents a synthetic route to produce chloramphenicol esters by taking advantage the high enantio- and regio-selectivity of lipases. A series of chloramphenicol esters were synthesized using chloramphenicol, acyl donors of different carbon chain length and lipase LipBA (lipase cloned from...

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Bibliographic Details
Main Authors: Fengying Dong, Lingmeng Li, Lin Lin, Dannong He, Jingwen Chen, Wei Wei, Dongzhi Wei
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Molecules
Subjects:
enzymatic catalysis
regioselectivity
chloramphenicol esters
green chemistry
Bacillus amyloliquefaciens
Online Access:https://www.mdpi.com/1420-3049/22/9/1523

Internet

https://www.mdpi.com/1420-3049/22/9/1523

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