Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation

Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation

Rabies, caused by rabies virus (RABV), is a fatal neurological disease that still causes more than 59,000 human deaths each year. Type III interferon IFN-λs are cytokines with type I IFN-like antiviral activities. Although IFN-λ can restrict the infection for some viruses, especially intestinal viru...

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Bibliographic Details
Main Authors: Yingying Li, Ling Zhao, Zhaochen Luo, Yachun Zhang, Lei Lv, Jianqing Zhao, Baokun Sui, Fei Huang, Min Cui, Zhen F. Fu, Ming Zhou
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
interferon-λ
rabies virus
interferon-stimulated genes
inflammation
blood-brain barrier
Online Access:https://www.mdpi.com/1999-4915/12/4/405

Internet

https://www.mdpi.com/1999-4915/12/4/405

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