Myeloid-Derived Suppressor Cells: A Multifaceted Accomplice in Tumor Progression

Myeloid-derived suppressor cell (MDSC) is a heterogeneous population of immature myeloid cells, has a pivotal role in negatively regulating immune response, promoting tumor progression, creating pre-metastases niche, and weakening immunotherapy efficacy. The underlying mechanisms are complex and div...

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Bibliographic Details
Main Authors: Jia-Nan Cheng, Yi-Xiao Yuan, Bo Zhu, Qingzhu Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.740827/full