Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts

Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts

Sirt-3 is an important regulator of mitochondrial function and cellular energy homeostasis, whose function is associated with aging and various pathologies such as Alzheimer’s disease, Parkinson’s disease, cardiovascular diseases, and cancers. Many of these conditions show differences in incidence,...

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Bibliographic Details
Main Authors: Robert Belužić, Ena Šimunić, Iva I. Podgorski, Marija Pinterić, Marijana Popović Hadžija, Tihomir Balog, Sandra Sobočanec
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
Sirtuin 3
sex differences
mouse embryonic fibroblasts
Hif-1α
integrated stress response
unfolded protein response
Online Access:https://www.mdpi.com/1422-0067/25/7/3868

Internet

https://www.mdpi.com/1422-0067/25/7/3868

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