Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.

Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.

Lung adenocarcinoma (LAD) has extreme genetic variation among patients, which is currently not well understood, limiting progress in therapy development and research. LAD intrinsic molecular subtypes are a validated stratification of naturally-occurring gene expression patterns and encompass differe...

Full description

Bibliographic Details
Main Authors: Matthew D Wilkerson, Xiaoying Yin, Vonn Walter, Ni Zhao, Christopher R Cabanski, Michele C Hayward, C Ryan Miller, Mark A Socinski, Alden M Parsons, Leigh B Thorne, Benjamin E Haithcock, Nirmal K Veeramachaneni, William K Funkhouser, Scott H Randell, Philip S Bernard, Charles M Perou, D Neil Hayes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3349715?pdf=render

Internet

http://europepmc.org/articles/PMC3349715?pdf=render

Similar Items