Fusion of ZMYND8 and RELA genes in acute erythroid leukemia.

Acute erythroid leukemia was diagnosed in a 4-month-old boy. Cytogenetic analysis of bone marrow (BM) cells showed a t(11;20)(p11;q11) translocation. RNA extracted from the BM was sequenced and analyzed for fusion transcripts using the software FusionMap. A ZMYND8-RELA fusion was ranked first. RT-PC...

Full description

Bibliographic Details
Main Authors: Ioannis Panagopoulos, Francesca Micci, Jim Thorsen, Lisbeth Haugom, Jochen Buechner, Gitte Kerndrup, Anne Tierens, Bernward Zeller, Sverre Heim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646816?pdf=render