Optimization of composite cryoprotectant for freeze-drying Bifidobacterium bifidum BB01 by response surface methodology

Freeze drying has been well applied in the preparation of high-efficiency probiotic powders. However, the process is generally accompanied by probiotic viability deficiency, which is the bottleneck for further application. To improve the viability of Bifidobacterium bifidum BB01 during freeze-drying...

Full description

Bibliographic Details
Main Authors: He Chen, Mengqi Tian, Li Chen, Xiuxiu Cui, Jiangpeng Meng, Guowei Shu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1603157