Cardiac myosin activators for heart failure therapy: focus on omecamtiv mecarbil

Heart failure continues to be a major global health problem with a pronounced impact on morbidity and mortality and very limited drug treatment options especially with regard to inotropic therapy. Omecamtiv mecarbil is a first-in-class cardiac myosin activator, which increases the proportion of myos...

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Bibliographic Details
Main Authors: Edgardo Kaplinsky, Gordon Mallarkey
Format: Article
Language:English
Published: BioExcel Publishing Ltd 2018-04-01
Series:Drugs in Context
Subjects:
Online Access:http://www.drugsincontext.com/cardiac-myosin-activators-for-heart-failure-therapy-focus-on-omecamtiv-mecarbil